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Metagenics AdvaClear supports daily detoxification for optimal vitality and health. This formula provides methylated B12 and folate along with bifunctional nutritional support designed to enhance the activities of several liver detoxification enzymes and support Phase I and Phase II detoxification pathways




  • Promotes overall well-being by supporting balanced hepatic detoxification
  • Features enhanced bifunctional detoxification support with key phytonutrients , methylatedvitamin B12, and calcium L-5-methyltetrahydrofolate, a bioavailable folate
  • Provides antioxidant protection against reactive oxygen intermediates produced during the detoxification process
  • Gluten Free
  • Non-GMO


Usage Instructions:

Adults take one capsule 3 times daily with meals or as directed by your healthcare practitioner. Take a few hours before or after taking other medications. Use for a minimum of 3 weeks to see beneficial effects.




Daily Value

Artichoke (Cynara scolymus L.) 10:1 leaf extract equivalent to 830 mg of artichoke

83 mg


Vitamin C (ascorbic acid)

66 mg


Watercress (Nasturtium officinale) 4:1 aerial parts extract equivalent to 264 mg of watercress

66 mg



58 mg


Milk Thistle (Silybum marianum) seed extract standardized to 50% silymarin

50 mg


Pomegranate (Punica granatum) whole fruit extract standardized to 40% ellagic acid

42 mg



33 mg


Green tea (Camellia sinensis) leaf extract standardized to 60% catechins and 40% EGCG

28 mg


Vitamin E (d-alpha-tocopheryl succinate)

22 mg


Pantothenic Acid (calcium d-pantothenate)

16.5 mg


Vitamin B6 (pyridoxine HCl)

8 mg



6.6 mg


Thiamin (thiamin mononitrate)

5 mg



5 mg


Zinc (zinc citrate)

3 mg



2.5 mg


Manganese (manganese citrate)

0.83 mg



500 mcg


Copper (copper citrate)

0.33 mg


Folate (calcium L-5-methyltetrahydrofolate)

134 mcg


Vitamin A (retinyl palmitate)

125 mcg


Molybdenum (hydrolyzed vegetable protein)

33 mcg



33 mcg


Selenium (selenomethionine)

25 mcg


Vitamin B12 (méthylcobalamine)

16.6 mcg


Vitamin D (cholecalciferol)

0.42 mcg



Non-Medicinal Ingredients: Hypromellose, cellulose, sodium sulfate, magnesium stearate (veg.), and silicon dioxide.


Caution: Consult a healthcare practitioner if you have gallstones, kidney stones, an iron deficiency, liver disorder or develop symptoms of liver trouble, or if symptoms persist or worsen. If pregnant, breast-feeding, or are taking nitroglycerin or antibiotics, consult a healthcare practitioner. Do not use if you have a bile duct obstruction or are allergic to plants of the Asteraceae/Compositae/Daisy family. People sensitive to nicotinic acid may experience flushing of the skin that is generally mild and transient. Hypersensitivity (e.g. allergy) has been known to occur; in which case, discontinue use. Consult a healthcare practitioner for use beyond 12 weeks. For adult use only. Do not use if perma seal is missing.